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20 Most Poisonous Snakes in the United States

a snake that is laying on the ground
a snake that is laying on the ground. Image via Unsplash.

The United States is home to a fascinating array of biodiversity, and among this diversity are some of the most venomous snakes in the world. While these creatures are often feared, they play a vital role in maintaining the ecological balance. Through understanding and knowledge, we can learn to respect their space and minimize the risks of encounters. In this article, we explore the 20 most poisonous snakes found across the United States, delving into their habitats, behaviors, and the importance of their preservation.

20. Cottonmouth (Agkistrodon piscivorus)

brown and black snake on gray concrete floor during sunset
Cottonmouth. Image via Unsplash

Cottonmouths, also known as water moccasins, are semi-aquatic vipers found primarily in the southeastern United States. Known for their distinctive white mouth, which they display as a warning, these snakes inhabit swamps, marshes, and streams. Their venom contains hemotoxins that can destroy tissue and cause severe internal damage.

19. Eastern Diamondback Rattlesnake (Crotalus adamanteus)

A snake that is laying down in the grass
Eastern Diamondback Rattlesnake. Image via Unsplash

The Eastern Diamondback is the largest rattlesnake species and can be found in the coastal plains from North Carolina to Louisiana. Recognized by its diamond-shaped pattern, this snake uses its potent venom to subdue prey. Its bites can be life-threatening, requiring immediate medical attention.

18. Coral Snake (Micrurus fulvius)

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Coral Snakes. Image via Pixabay

Coral snakes are elusive and spend much of their time underground. Their bright red, yellow, and black bands serve as a warning to potential predators. Native to the southeastern United States, they possess powerful neurotoxins that can cause respiratory failure if untreated.

17. Timber Rattlesnake (Crotalus horridus)

black and white snake skin
Timber Rattlesnake. Image via Unsplash

This species is widespread across the eastern United States, inhabiting deciduous forests. Timber rattlesnakes are known for their patient hunting style, striking quickly with their hemotoxic venom to immobilize prey. Their populations are currently threatened by habitat destruction.

16. Mojave Rattlesnake (Crotalus scutulatus)

Mojave Rattlesnake.
Mojave Rattlesnake. Image via Depositphotos.

Found primarily in the deserts of the southwestern United States, the Mojave rattlesnake is notorious for its potent venom, which contains both neurotoxins and hemotoxins. This snake is adept at regulating its venom dose, making it particularly dangerous to humans.

15. Pygmy Rattlesnake (Sistrurus miliarius)

brown and black snake on brown tree branch
Pygmy Rattlesnake. Image via Unsplash

Pygmy rattlesnakes are small but formidable, found in the southeastern United States from Florida to eastern Mississippi. Their rattle is much softer, and they rely on camouflage for protection. Though their venom is not as potent, it can still cause significant discomfort and swelling.

14. Western Diamondback Rattlesnake (Crotalus atrox)

Western Diamondback Rattlesnake
Western Diamondback Rattlesnake native to the southwestern United States. Grows to a length of 6 feet. Image via Depositphotos.

This is one of the most common rattlesnakes in the United States, found across the southwestern regions. Known for its aggressive defense mechanisms, its venom can cause extensive tissue damage. They play a crucial role in rodent population control.

13. Copperhead (Agkistrodon contortrix)

A snake that is laying on the ground
Copperhead. Image via Unsplash

Copperheads are widespread across the eastern and central United States, characterized by their distinctive hourglass pattern. Their venom is less potent compared to other snakes in the United States, but a bite can still be extremely painful and requires medical attention.

12. Eastern Coral Snake (Micrurus fulvius)

coral snake
Coral snake. Image by Norman.benton, CC BY-SA 3.0 https://creativecommons.org/licenses/by-sa/3.0, via Wikimedia Commons

Often confused with the non-venomous king snake, the Eastern Coral snake can be identified by its color pattern: red, yellow, black. Though they rarely bite humans, their neurotoxic venom, when they do, can be fatal without prompt intervention.

11. Western Rattlesnake (Crotalus viridis)

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Western Rattlesnake. Image via Unsplash

The Western rattlesnake can be found throughout the western half of the United States, thriving in a range of habitats from deserts to woodlands. Its hemotoxic venom is strong enough to incapacitate prey quickly, and they are noted for their coiled, ready-to-strike posture when threatened.

10. Prairie Rattlesnake (Crotalus viridis viridis)

white and brown snake on brown sand
Prairie Rattlesnake. Image via Unsplash

This species roams the Great Plains of the United States. The Prairie rattlesnake is adaptable and has been seen in grasslands, deserts, and pine forests. Their venom, while not the most lethal, can cause severe pain, swelling, and possible tissue damage.

9. Canebrake Rattlesnake (Crotalus horridus)

a close up of a snake on a rock
Canebrake Rattlesnake. Image via Unsplash

Commonly found in the lowland areas of the southeastern United States, the Canebrake rattlesnake shares a habitat similar to that of the timber rattlesnake. They possess long fangs and can deliver a significant amount of venom, necessitating swift medical assistance post-bite.

8. Arizona Black Rattlesnake (Crotalus cerberus)

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Arizona Black Rattlesnake. Image via Unsplash

Primarily found in central Arizona, the Arizona black rattlesnake is known for its dark pigmentation which provides excellent camouflage against rocky terrain. While its venom is not the most potent, a bite can cause intense pain and requires medical treatment.

7. Banded Rock Rattlesnake (Crotalus lepidus klauberi)

black and white snake on tree branch
Banded Rock Rattlesnake. Image via Unsplash

Inhabiting the mountain ranges of the southwestern United States, the Banded rock rattlesnake is adept at blending into its rocky surroundings. While relatively shy, its hemotoxic venom can cause discomfort and medical issues if bitten.

6. Massasauga (Sistrurus catenatus)

brown snake
Eastern massasauga. Image via Unsplash

The Massasauga is a small rattlesnake that inhabits wetlands in the Great Lakes region and parts of the Midwest. Its venom is potent enough to make it dangerous despite its small size. They are a federally threatened species, highlighting the need for conservation efforts.

5. Sidewinder (Crotalus cerastes)

brown and black snake on brown wooden stick
Sidewinder. Image via Unsplash

Navigating the sands of the Mojave and Sonoran deserts, the Sidewinder is unique for its distinctive sideways locomotion. It uses its venom to quickly subdue small prey, and while its bite is venomous to humans, fatalities are rare with prompt treatment.

4. Northern Pacific Rattlesnake (Crotalus oreganus oreganus)

a close up of a snake on a leaf
Northern Pacific Rattlesnake. Image via Unsplash

Found in the Pacific Northwest, the Northern Pacific rattlesnake prefers forested and grassland regions. Known for its varying color patterns, its venom is hemotoxic, resulting in symptoms such as swelling and pain in humans.

3. Cottonmouth (Western) (Agkistrodon piscivorus leucostoma)

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Western cottonmouth. Image via Pixabay

This variant of the cottonmouth is located in the central United States, predominantly around waterways and wetlands. As with other cottonmouths, they exhibit aggressive behavior when threatened, and their venom can cause serious tissue damage.

2. Tiger Rattlesnake (Crotalus tigris)

Rattle snake
A rattlesnake in Death Valley, California. Image via Tigerhawkvok (talk · contribs), CC BY-SA 3.0 https://creativecommons.org/licenses/by-sa/3.0, via Wikimedia Commons

Naming its territory in the southern deserts of Arizona and parts of Mexico, the Tiger rattlesnake is recognized by its narrow head and striking body pattern. Its venom is among the most potent of any rattlesnake, yet bites are rare due to its reclusive nature.

1. Speckled Rattlesnake (Crotalus mitchellii)

a close up of a snake on a rock
Speckled Rattlesnake. Image via Unsplash

This rattlesnake is found in semi-arid regions of the southwestern United States. Known for its variable color patterns that match its surroundings, the Speckled rattlesnake possesses venom that, while not the most toxic, warrants medical attention if bitten.

As intimidating as venomous snakes can be, these 20 species showcase a rich diversity and play significant roles in their ecosystems. They help control rodent populations and contribute to the biodiversity of their habitats. While human-snake encounters can be dangerous, understanding these creatures can aid in avoiding unnecessary conflict and supporting conservation efforts. In doing so, we maintain the ecological balance and appreciate the complex world of fauna around us.

Latest posts by Alana Theron, BSc in Biodiversity and Ecology (see all)